Aug 18, 2011 · Estradiol valerate plus dienogest (E2V/DNG) is now available in a four-phasic regimen that integrates an estrogen stepdown and progestin stepup dosing approach along with a short two-day hormone-free interval.
Aug 2, 2014 · Combined oral contraceptives formulated to include estradiol (E 2) have recently become available for the indication of pregnancy prevention